ÑÐ²Ð°ÑÑÐºÐ¸, Creative Commons Attribution-ShareAlike License, This page was last edited on 21 December 2020, at 11:14. Such products have a long history of use as â¦ According to the US Food and Drug Administration, the restriction of BA addition in general types of food is kept as 1000 mg kg− 1. As mentioned for other organic acids, antimicrobial activity is greatest at low pH. Linear Formula C 6 H 5 COOH . However, these methods are time-consuming with complicated pretreatments and require expensive instruments (Pylypiw and Grether, 2000). Benzoic acid is produced commercially by partial oxidation of toluene with oxygen. It can be synthesized by the cobalt or manganese catalyzed atmospheric oxidation of toluene. , In terms of its biosynthesis, benzoate is produced in plants from cinnamic acid. A minimum acidity is necessary therefore to block dissociation and to dissolve the acid from its salts when benzoates are used. Benzoic acid (BA) is a commonly used antimicrobial preservative in food and beverages, especially in carbonated beverages, as it presents its strongest antibacterial activity at pH 2.5–4.0. Benzoic acid's most common uses are in carbonated beverages, pickles, sauces, and jelly. 4-Carboxy-alpha-methylbenzeneacetic acid. Benzoic acid is most commonly found in industrial settings to manufacture a wide variety of products such as perfumes, dyes, topical medications and insect repellents. Benzoic acid was discovered in the sixteenth century. Figure 9.2. Tiny pieces of silica gel substrate were placed in an uncomplicated device that is made at home for conducting the TFME process and then determination of the BA content was done with the help of SERS after dropping colloidal gold onto the substrate. Synonyms. The dissociation constant is 6.46 × 10−5 (Bosund 1960 and 1962), which means that the pH that is reached applying lactic acid is already sufficient. The maximal antimicrobial activity of benzoic acid has been described between pH 2.5 and 4.5. The product contains significant amounts of chlorinated benzoic acid derivatives. C21H15AlO6. 3,5-dihydroxybenzoic acid methyl ester,benzoic acid, 3 Show more: PubChem CID: 75076: IUPAC Name: methyl 3,5-dihydroxybenzoate: SMILES: COC(=O)C1=CC(=CC(=C1)O)O: 5. Benzoic acid is not allowed in all countries. Benzoic acid, aluminum salt. The process is catalyzed by cobalt or manganese naphthenates. Benzoic acid â¥99.5%, FCC, FG CAS Number 65-85-0. Bromobenzene can be converted to benzoic acid by "carboxylation" of the intermediate phenylmagnesium bromide. , In Taipei, Taiwan, a city health survey in 2010 found that 30% of dried and pickled food products had benzoic acid. Molecular Formula. Benzoic acidâs salt (sodium benzoate) is commonly used as a pH adjustor and preservative in food, preventing the growth of microbes to keep â¦ Sulphur dioxide is of similar concern because of adverse reaction but it is now not used in ready-to-drink products that are likely to be purchased by local authorities. The total dose of benzoic acid is excreted within 10–14 hr and 75–80% is excreted within 6 hr. The authorisation and conditions of use of preservatives are governed in the European Union by Directive 95/2/EC of the European Parliament and Council of 20 February 1995 on Food Additives other than Colours and Sweeteners. Benzoic acid is a constituent of Whitfield's ointment which is used for the treatment of fungal skin diseases such as tinea, ringworm, and athlete's foot.  Cats have a significantly lower tolerance against benzoic acid and its salts than rats and mice. it is most often used in the form of sodium benzoate because of the low aqueous solubility of the free acid. Chemically, parabens are esters made by combining benzoic acid and alcohols such as methanol or propanol. The acceptable daily intake (ADI) for benzoic acid is 5 mg/kg body weight. Benzoic acid reacts with hydrogenating reagents to afford hexahydrobenzoic acid. Benzoic acid occurs naturally in many plants and serves as an intermediate in the biosynthesis of many secondary metabolites. Benzoic acid preservative prevents or delays nutritional losses due to microbiological, enzymatic, or chemical changes of foods â¦ The provision of appropriate labelling is accepted by the UK government as an appropriate way of notifying the public of the presence of food additives, thus enabling informed choice to be made by the consumer. 2-p-carboxyphenylpropionic acid. Parabens are antimicrobial compounds chemically derived from benzoic acid. Benzoic acid is an extensively used food preservative. Molecular Weight 122.12 . (1997) treated ionomer films with alkali. FEMA Number 2131 . Acidic food and beverage like fruit juice(citric acid), sparkling drinks (carbon dioxide), soft drinks(phosphoric acid), pickles(vinegar) or other acidified food are preserved with benzoic acid and benzoates. 4- (1-Carboxy-ethyl)-benzoic acid. Richard P. Pohanish, in Sittig's Handbook of Pesticides and Agricultural Chemicals (Second Edition), 2015, Benzoic acid, 2-[((((4,6-dimethyl-2-pyrimidinyl)amino)carbonyl)amino)sulfonyl]-, methyl ester; Benzoic acid, o-[(3-(4,6-dimethyl-2-pyrimidinyl)ureido)sulfonyl]-, methyl ester; Methyl 2-[((((4,6-dimethyl-2-pyrimidinyl)amino)carbonyl)amino) sulfonyl]benzoate; Sulfometuron methyl; Methyl 2-[((((4,6-dimethyl-2-pyrimidinyl)amino)carbonyl)amino) sulfonyl]benzoate, Philip R. Ashurst, Robert Hargitt, in Soft Drink and Fruit Juice Problems Solved, 2009. Benzoate also specifically inhibits amino acid uptake and certain enzymes within the cell: alpha-ketoglutarate, succinate dehydrogenase, 6-phosphofructo-2-kinase and lipase. Jakob Søltoft-Jensen, Flemming Hansen, in Emerging Technologies for Food Processing, 2005. It is necessary to use preservatives in some soft drinks to ensure the safety of the product by protecting it from spoilage micro-organisms.