A three-year study of college athletes found that those taking creatine had fewer cases of dehydration, muscle cramps, or muscle injuries than those not taking it. However, like most nutritional supplements, creatine supplements are not strictly regulated and thus can produce numerous, possibly dangerous, side effects. Information about possible side effects of N.O.-Xplode is largely unavailable. However, you will not experience any adverse effects with recommended doses. Kidney stones. ShaeLee Chatterton began writing professionally in 2007. Severe muscle cramps can deter the proper flow of blood, which strains the transfer of nutrients to muscles. According to MayoClinic.com, about 95 percent of the body's store of creatine is located in the skeletal muscles. Nutrex. Researchers noted that creatine reduced cramping incidents by 60% (13). Brands include GNC Pro Performance Creatine Monohydrate and NOW Sports Creatine Monohydrate Powder. It is then transported through the blood to the muscles. Learn about when to take creatine to maximize its impressive benefits. I've heard alot of bs about kidney failures etc. As with many supplements or medications, excessive doses may cause digestive issues. However, your diet and natural creatine levels do not normally maximize muscle stores of this compound. That said, creatine supplements should be approached with caution if you have a history of liver or kidney issues. However, this idea is not supported by any evidence. Dizziness 5. Few adverse reactions have been reported in clinical studies among patients with neurological or muscle disorders, or in healthy individuals.Concerns regarding kidney and liver toxicity exist; clear proof of safety is lacking and caution is warranted.Case reports of adverse reactions among athletes include dehydration, electrolyte imbalance, and muscle cramping. During high-intensity exercise, the stored creatine helps your muscles produce more energy. Around 95% of the creatine in your body is stored in your muscles. Creatine has been used for more than a century, and over 500 studies support its safety and effectiveness. If you are experiencing serious medical symptoms, seek emergency treatment immediately. 4 people found this helpful “Creatine monohydrate is the exact compound that more than 95 percent of the studies used, so why take a chance on another compound from a safety and effectiveness perspective?” Tarnopolsky says. Dymatize. The main issues with creatine monohydrate are its solubility in fluids and its absorption by the body. GNC Pro Performance® Creatine Monohydrate - Unflavored 62. Bloating. Virtually No Side Effects. This may lead to lower muscle mass rather than the desired higher muscle mass. Rate this treatment and share your opinion! I'm very curious about GNC's creatine product. A severe case of diarrhea may also lead to electrolyte imbalances and dehydration. Here are 10 graphs that show the power of creatine. Journal of International Society of Sports Nutrition. 2017; 14: 18. MayoClinic.com explains, weight that is gained through use of creatine is because of water retention. Fact: There is no data that shows creatine causes muscle cramps or dehydration. Creatine monohydrate is known to cause water retention and as a result, causes frequent headaches throughout the day. Dehydration 7. Although most healthy people can take it with no problem, creatine can, in rare cases, have adverse effects, particularly when used in excess. The creatine found in GNC AMP Creatine HCL 189™ is an advanced, clinically studied form called polyethylene glycosylated creatine – or PEG Creatine HCL. To date, no study of creatine use in healthy individuals has provided evidence of harm to these organs (1, 22, 23, 24, 25, 26). Creatine can help improve blood sugar management, so if you are using medication known to affect blood sugar, you should discuss creatine use with a doctor (5). There is no evidence that it causes adverse conditions like rhabdomyolysis or compartment syndrome. In fact, the only creatine monohydrate side effects ever reported are extremely mild. Healthline Media does not provide medical advice, diagnosis, or treatment. Myth 3: Creatine Causes Cramping and Dehydration. This article explains how creatine can improve your exercise…. Here's a review of the top six types, including which one is best. Product: Unflavored, Creatine Monohydrate (2.2 lbs), 5g Per serving, 200 servings First thought: Creatine is the number-one sports performance supplement available. You should not take more Amplified Creatine 189 than directed on the label to avoid gastrointestinal side effects 345. 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