Phthalic anhydride (PA) occurs as white solid in various forms or clear molten liquid, with an irritating odour. Phthalic anhydride is widely used in organic syntheses for the manu- Phthalic anhydride can also be prepared from phthalic acid by simple thermal dehydration.[4]. Synonym: 1,3-Isobenzofurandione Chiral alcohols form half-esters (see above), and these derivatives are often resolvable because they form diastereomeric salts with chiral amines such as brucine. It can also be produced by ammoxidation of o-xylene. Phthalic anhydride in the form of vapor, fume, or dust irritates the eyes. Phthalate esters are derived from phthalic anhydride by the alcoholysis reaction. Balaji Santhanam. Incompatible with acids, strong oxidizing agents, alcohols, amines, and bases. Vapor pressure is < 0.3 Pa at 20 ° C. In presence of water phthalic anhydride hydrolyzes to phthalic acid. Expired - Lifetime Application number US31013A Inventor Metro D Kulik [4] The overall process involves oxidative cleavage of one of the rings and loss of two of the carbon atoms as carbon dioxide. University of Georgia, Athens, GA 30602. Phthalic Anhydride (PA) White scaly or Crystalline powder, Molecular formula C8H403, Molecular weight 148.12, Melting point 131.1l , Boiling point 284.5 , Flash point 151 (close), 165 (open), Spontaneous combustion point 584 , Density (Solid) 1.527g / cm3, insoluble in water, soluble in water, alcohol, ether, benzene and most organic solvents. [4] In the 1980s, approximately 6.5×109 kg of these esters were produced annually, and the scale of production was increasing each year, all from phthalic anhydride. Inhalation Remove to fresh air. PA is soluble in alcohol and carbon disulphide. Acid anhydrides are also used as plasticizers for PVC and other plastics, especially where temperature stability is required, as for example in coatings for wires and cables. This colorless solid is an important industrial chemical, especially for the large–scale production of plasticizers for plastics. Phthalic acid is an aromatic dicarboxylic acid, with formula C 6 H 4 (CO 2 H) 2.It is an isomer of isophthalic acid and terephthalic acid.Although phthalic acid is of modest commercial importance, the closely related derivative phthalic anhydride is a commodity chemical produced on a large scale. +Add Attachment 2.01.2.2.2 Anhydrides. An alternative process involves oxidation of the two methyl groups of o-xylene, a more atom-economical process. If not breathing give artificial respiration consult a physician. [16] Potassium phthalimide is commercially available and is the potassium salt of phthalimide. It is both an irritant and sensitizer of the skin and respiratory tract, and may produce asthma on repeated exposure. Search for more papers by this author. Phthalic Anhydride (PA) is used as the major ingredient in the manufacture of plasticizers, unsaturated polyester resin, paint and others. Studies show that exposure to phthalic anhydride can cause rhinitis, chronic bronchitis, and asthma. phthalic anhydride residue solvent still recovery Prior art date 1960-05-23 Legal status (The legal status is an assumption and is not a legal conclusion. Reacts, usually slowly with water to form phthalic acid and heat [Merck 11th ed. It is the anhydride of phthalic acid. Phthalic anhydride is the anhydride of phthalic acid. : 85-44-9 MSDS SECTION 1: Identification of the substance/mixture and of the company/undertaking Phthalic Anhydride. This colourless solid is an important industrial chemical, especially for the large-scale production of plasticizers for plastics. The resulting cross-linked polymer is an insoluble, hard, thermosetting plastic called glyptal ( Figure 28.12 ). : 85-44-9 1.2 Relevant identified uses of the substance or mixture and uses advised against Identified uses : Laboratorychemicals, Industrial & for professional use only. First Aid Measures Inhalation: MAY BE FATAL IF INHALED. Alternatively, it may be prepared by treating the anhydride with ammonium carbonate or urea. Geert‐Jan Boons. Get medical attention. Metro D 0315: 1,2-Benzenedicarboxylic acid anhydride 1,3-Isobenzofurandione: June 2003 I.K para-chlorophenol followed by hydrolysis of the methyl. 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