The following properties have been highlighted as critical: The substance properties displayed in this section (with the exception of PBT properties) are derived from harmonised classification and labelling (CLH) and/or REACH registered dossier information. Melting point, 105.5°C. Under specific conditions, a registrant can claim confidentiality of their identity. Organic Acids Other Organic Acids Carbon atoms Common name Chemical formula Common location pKa 3 Lactic acid CH3CH ... 3 Glutaric acid 4.34 5.41 4 Adipic acid 4.41 5.41 5 Pimelic acid 4.50 5.43 6 Subericacid 4.53 5.50. Long-term EC10 or LC10 or NOEC for soil microorganisms provides substance information on the substance’s effect concentration or lethal concentration (long term) for 10% of the soil microorganisms in the test, or the no observed effect concentration for soil microorganisms. LC50 for freshwater fish provides substance information on the substance’s lethal concentration for 50% of the freshwater fish in the test, displayed in milligram per litre. This section summarises the values related to toxicity to soil macroorganisms (except arthropods) from all registered dossiers for the substance. Displayed in all cases is the MOST CONSERVATIVE of the value(s) provided, ranking in the order as below. All mass spectra in this site (plus many more) are available from the NIST/EPA/NIH Mass Spectral Library. Solubility in organic solvents / fat solubility. If so, the data provided is not processed for the Brief Profile. Short-term EC50 or LC50 for terrestrial plants provides substance information on the substance’s effect concentration or lethal concentration (short term) for 50% of the terrestrial plants in the test, generally displayed in milligram per kilo soil (dry weight). The % is based on count of values provided. Data is generally displayed in milligrams per kilogram in the case of soil (dry/wet weight), or gram per hectare. Since a two dimensional chemical structure can be drawn in various ways, there are several correct SMILES notations for one molecule. Pimelic acid is the organic compound with the formula HO 2 C(CH 2) 5 CO 2 H. Derivatives of pimelic acid are involved in the biosynthesis of the amino acid called lysine.Pimelic acid is one methylene longer than a related dicarboxylic acid, adipic acid, a precursor to many polyesters and polyamides.. Pimelic acid has been synthesized from cyclohexanone and from salicylic acid. Due to the quantity of information and the number of chemicals, the Brief Profile is automatically generated based on the information available and is not manually verified. EC10 / LC10 or NOEC for marine water algae provides substance information on the substance’s effect concentration/lethal concentration for 10% of the tested marine water algae or the no observed effect concentration for marine water algae. Within each of these categories, data is prioritised further by duration (in hours), with longer prioritised over shorter. 75650-93-0 - UKCSFKLWNHUBDY-BYPYZUCNSA-N - alpha-Amino-epsilon-keto-pimelic acid - Similar structures search, synonyms, formulas, resource links, and other chemical information. EC10 / LC10 or NOEC for marine fish provides substance information on the substance’s effect concentration/lethal concentration for 10% of the tested freshwater fish or the no observed effect concentration. RST is the consecutive number of the substance in the series ABC. Data is generally displayed in milligrams per kilogram bodyweight per day. The BPR regulatory processes identified for the Brief Profile are: Prior Informed Consent (PIC)The PIC Regulation (649/2012) entered into force on 4 July 2014. the minimum numerical value associated with the highest priority picklist item. Registrants can register their substance’s oxidising properties as: Note: Registrants can also select ‘other’ as the oxidising value for their substance. By summarising the endpoint study data, ECHA aims to make this information accessible in a user-friendly way in line with the Agency’s goals and standards. Pimelic acid, also known as heptanedioic acid is a dicarboxylic acid. Short-term EC50 or LC50 for birds provides substance information on the substance’s effect concentration or lethal concentration (short term) for 50% of birds in the test, generally displayed in milligram per kilo food. Processable data for summary is prioritised by test species (see list below) and subsequently further prioritised by the dose descriptor. BOD5/COD ratio provides substance information on the substance’s BOD5/COD ratio values displayed in O2 (milli)gram per gram test material. This section summarises the melting and freezing point values from all registered dossiers for the substance. ABC corresponds to the atomic number of the most characteristic element or the most characteristic organic group in the molecule. The ‘Scientific properties’ section gives an overview of summarised scientific data from registered dossiers. See the official IUPAC website for more information on the International Union of Pure and Applied Chemistry. Therefore the quality of these names may be variable. EC/LC50 for freshwater plants provides substance information on the substance’s effect concentration or lethal concentration for 50% of the freshwater plants in the test, generally displayed in milligram per litre. Processable data for study results is prioritised by dose descriptor type (see list below) and subsequently further prioritised by the test species. Half-life in sediment provides substance information on the substance’s half-life in sediment in seconds/minutes/hours/days/weeks/months/years at a temperature measured in °C.Note: Results without a measurement condition (temperature) are not processed for the Brief Profile. Pre-registration allows companies to continue manufacturing and importing their. In this case, the preferred CAS number is displayed first. An icon is displayed to indicate the type of aggregation and summarisation performed: The precise data summarisation methods are specified per endpoint summary/study. Please upgrade your Internet Explorer to a newer version. The information provided in the free-text fields is not published in the Brief Profiles. Relative density at 20 °C provides information on the substance relative density at 20 °C. The goal of CLP is to make sure that hazards presented by chemicals are clearly communicated to workers and consumers in the European Union through a system of classifying and labelling of chemicals. This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications. This information has not been reviewed or verified by ECHA, and may change without prior notice. Autoflammability / Self-ignition at 101 325 Pa provides substance information on the substance’s self-ignition temperature in °C at a pressure of 101 325 Pa. Thirdly the display of data is prioritised by units. Note: Registrants can also select ‘BMD’, ‘BMC’, ‘dose level’ and ‘conc. This section summarises the values related to hydrolysis from all registered dossiers for the substance. The percentage is based on the count of values provided. Welcome to the ECHA website. for charge, stereo–chemical and/or isotopic information. Displayed is the most conservative of the prioritised value(s). This section provides information on the recommended measures to minimise or prevent adverse effects resulting from exposure to a hazardous product, or improper storage or handling of a hazardous product. The Brief Profile summarises the non-confidential data on substances as it is held in the databases of the European Chemical Agency (ECHA), including data provided by third parties. If you believe you are experiencing an interaction, contact a healthcare provider immediately. This section summarises the values related to Henry’s law constant (H) from all registered dossiers for the substance. Displayed is the MOST CONSERVATIVE of the value(s) provided, ranking in the order as below. The quality and correctness of the information remains the responsibility of the data submitter. Classifications under REACH have to be supported by data (support studies). This section summarises the values related to biodegradation in soil from all registered dossiers for the substance. Note: Registrants can also select ‘other’ as a reaction type for the degradation rate constant of the substance. Since the source data can be updated at any time while the Brief Profiles are updated at intervals, a slight delay in the publication of information may occur. the level of agreement, in substance classification between the REACH registrants (dark blue bar) and CLP notifiers (light blue bar), as well as between the notified classifications and the approved harmonised classification. 28664-02-0. Information in the ‘Scientific properties’ section is structured by substance properties, further broken down into endpoints. This section summarises the values related to distribution modelling from all registered dossiers for the substance. BOD5 provides substance information on the substance’s BOD5 values displayed in O2 (milli)gram per gram test material. The Agency thus cannot guarantee the correctness of the information displayed. The source of the information is mentioned in the introductory sentence of the hazard statement. For accuracy reasons, substance manufacturers and importers are responsible for consulting official sources. Data is generally standardised and displayed in milligram per litre or molar per litre. Values are generally displayed in milligram per litre. Information on this page: Mass spectrum (electron ionization) References; Notes US2673219A US195484A US19548450A US2673219A US 2673219 A US2673219 A US 2673219A US 195484 A US195484 A US 195484A US 19548450 A US19548450 A US 19548450A US 2673219 A US2673219 A US 2673219A Authority US United States Prior art keywords tetrahydrobenzaldehyde pimelic acid delta weight parts Prior art date 1949-11-19 Legal status (The legal status is an … This section displays all the public names and other identifiers available in ECHA's databases for the substance. This section summarises the values related to aquatic/sediment bioaccumulation in all registered dossiers for the substance. If more than one numerical result is available per endpoint, the range of results (min-max, RANGE method) will be displayed. After evaluation, proposals may be made for further regulatory action regarding the substance. The CLP Regulation makes sure that the hazards presented by chemicals are clearly communicated to workers and consumers in the European Union. 215–540–4, is covered by three harmonisations – 005–011–00–4; 005–011–01–1; 005–011–02–9), CLH information cannot be displayed in the Brief Profile as the differences between the CLH classifications require manual verification. Suspendisse porttitor leo quis purus porttitor posuere sit amet sit amet nunc. The Candidate List includes substances that are subject to additional protocols and reporting obligations and which may eventually be included in the Authorisation list, further limiting their use. As its name indicates, it is a major component of the oil from the fruit of oil palms ().Palmitic acid can also be found in meats, cheeses, butter, and other dairy products. Data from all dossiers registered and the Classifications and Labelling Inventory (C&L) for the same substance are used to generate the Brief Profile. Values are generally displayed in milligram per litre. If so, the data provided is not processed for the Brief Profile. Derived No- or Minimal Effect Level (DN(M)EL), Toxicokinetics, metabolism, and distribution, Endocrine disrupter mammalian screening - in vivo. Authorisation list (Annex XIV) – indicates if the substance is included in the Authorisation List. Though the Agency aims to include as many studies as possible in the Brief Profile endpoint study results/summaries, those studies which do not fit the format or miss crucial information (such as measurement conditions) cannot be processed and therefore will not be included on this page. The availability of additional data beyond the five results displayed is indicated by (…). This substance is used in the following activities or processes at workplace: transfer of chemicals, closed batch processing in synthesis or formulation, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure and transfer of substance into small containers. Additionally, if registrants select ‘other’ as a unit of measure for pressure, the measurement conditions (and therefore the study results) cannot be processed in the Brief Profile. 1.6), oxidising: maximum burning rate equal or higher than reference mixture, oxidising: vigorous reaction in preliminary test. Palmitic acid, or hexadecanoic acid in IUPAC nomenclature, is the most common saturated fatty acid found in animals, plants and microorganisms. LC50 for freshwater algae provides substance information on the substance’s lethal concentration for 50% of the freshwater algae in the test, displayed in generally milligram per litre. The data presented in these sections has been cleaned to remove names of one character or less, or names which consist solely of punctuation or numerical characters. Sed elementum odio augue, eget iaculis lorem faucibus vel. Please note that the information provided in the free-text fields is not published in the brief profiles. The regulation aims improve the protection of human health and the environment from the risks that can be posed by chemicals, while enhancing the competitiveness of the EU chemical industry. EC50/LC50 for microorganisms provides substance information on the substance’s effect concentration or lethal concentration for 50% of the microorganisms in the test, generally displayed in milligram per litre. REACH registration dossiers have greater data requirements (support studies) than notifications under CLP. Harmonised C&L– indicates if a European Union harmonised classifications and labelling has been assigned to the substance according to Annex VI to CLP and subsequent ATPs. Labeling and inhibitor studies show that pimelic acid is made by the fatty acid synthetic pathway. This section provides toxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. Other relevant information includes the following: To see the full list of notified classifications and have more information on impurities and additives relevant to classification, you can consult the C&L Inventory. Inherently biodegradable, fulfilling specific criteria; Inherently biodegradable, not fulfilling specific criteria, Under test conditions no biodegradation observed. Only non-confidential use descriptors are displayed and for readability purpose only use descriptors occurring in more than 5% of the total occurrences are displayed. Displayed are the RANGES of min – max of the PRIORITISED value(s) within the five highest priority groupings of provided data. Trade names gives all public trade names submitted to ECHA in REACH registrations. Aliquam nec erat semper, suscipit libero et, bibendum mauris. This section summarises the vapour pressure values from all registered dossiers for the substance. Free pimelic acid is a key intermediate of biotin synthesis in Bacillus subtilis. This section provides information on suppliers, importers or manufacturers of a substance (active and inactive) that have to register their substance under REACH. No or insufficient data available at present, Hazard related to composition of atmosphere identified, No potential to cause toxic effects if accumulated (in higher organisms) via the food chain, bw/day (mg/kg bw/day; mg/kg bw/day; mg/kg bw/day), DMEL (Derived Minimum Effect Level) - not included for short–term effects, Insufficient data available (further information necessary), Hazard unknown (no further information necessary), Hazard unknown but no further hazard information necessary as no exposure expected, ‘No DNEL required: short term exposure controlled by conditions for long-term’ is added, Hamster (combine hamster, Armenian; hamster, Chinese and hamster, Syrian), No adverse effect observed (not irritating), Adverse effect observed (irreversible damage), mg/kg bw/day (nominal/actual dose received), See ‘Study results oral: Prioritization by test species’, mg/L air (combining mg/L air, mg/L air (nominal), mg/L air (analytical), mg/m³ air, mg/m³ air (nominal), mg/m³ air (analytical)), ppm (combine ppm, ppm (nominal), ppm (analytical), mg/kg bw/day (actual dose received), mg/kg bw/day (combining mg/kg bw/day (nominal), mg/kg bw/day (actual dose received) and mg/kg bw/day), mg/cm² per day (combining mg/cm² per day, mg/cm² per day (nominal), mg/cm² per day (analytical)), No study available / no study available (further information necessary). Vivamus mauris lorem, fringilla at diam a, laoreet consequat eros. BOD5*100/COD provides substance information on the substance’s BOD5*100/COD values displayed in O2 (milli)gram per gram test material. This section summarises the Ecotoxicological information provided from all registered dossiers for the substance. Processable data is prioritised by the toxicity descriptor type (see list below) and subsequently further prioritised by duration (longer prioritised over shorter). See ‘Summary effect on fertility oral route’, except: This section displays the values related to neurotoxicity from all registered dossiers for the substance. If so, the data provided is not processed in the Brief Profile. Bioaccumulation factor (terrestrial species) provides substance information on the substance’s terrestrial bioaccumulative properties not taking account the dimensions. Registrant can provide information on eye exposure by selecting one of the following hazard assessment conclusions: Data for general population – eye exposure provides information on the substance’s hazard assessment conclusions regarding eye exposure (for the general population). Notification – indicates that notified C&L’s have been submitted to ECHA for a substance. Inhalation exposure provides information on the substance’s hazard assessment conclusions regarding inhalation exposure. Displayed are the RANGES of min – max of the PRIORITISED value(s) within the five highest priority groupings of provided data. Displayed are the RANGES of min – max of the PRIORITISED value(s) within the five highest priority groupings of provided data. If more than one type of substance is registered, both types will be displayed. The POPs regulatory processes identified for the Brief Profile are: Classification, Labelling and Packaging (CLP)The CLP Regulation (1272/2008) entered into force on 20 January 2009. 2020 © Copyrights BroadPharm. Derivatives of pimelic acid are involved in the biosynthesis of the amino acid called lysine. Release to the environment of this substance can occur from industrial use: manufacturing of the substance. pimelic acid (3,4,5-trimethoxybenzylidene)-hydrazide 1 Product Result | Match Criteria: Product Name ECHA has no public registered data on the routes by which this substance is most likely to be released to the environment. The date of the last update corresponds to the publication date of the Brief Profile and not necessarily to the date in which the update occurred in the source data (registered dossiers, the C&L Inventory or a regulatory process). If you have any comments or suggestions, please contact ECHA using our contact form. 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