hubrecht.eu. Sara is now working as a computational biologist in the lab of Jop Kind at the Hubrecht Institute (Netherlands). Online event. Jop Kind obtained his PhD from the Radboud University in Nijmegen for his work on dosage compensation in the lab of Asifa Akhtar at the EMBL Heidelberg. Past events. The researchers in Kind’s group will use the ERC grant to further research when and how cells make these identity choices. Read the new partnership agreement between Pontiac School District and the state including exhibits of data on the schools achievement gaps. Save the date for our Annual Conference! Network. This is particularly difficult to study because DSBs occur randomly in the genome, thus every single cell harbors a different DSB-landscape. Further, in the same cells, we also profile genome-wide chromatin states with a chromatin immunocleavage (ChIC) approach to study the relationships between DSB-repair and the local chromatin environment (. The John Kendrew Young Scientist Award (JKA) was launched in 2007 as an initiative from the EMBL Pensioner’s Association to honour EMBL’s first Director General, Sir John Kendrew (1975-1982), and to support scientists in the early stages of their career. Single cell epigenomics. Fingerprint. … 2016: Group Leader, Hubrecht Institute, Utrecht, The Netherlands. Hubrecht Institute. Researchers of the Hubrecht Institute (KNAW) in Utrecht, The Netherlands, and the MRC Laboratory of Molecular Biology in Cambridge, United Kingdom, have discovered a new way in which the human body repairs DNA damage caused by a degradation product of alcohol. We are particularly interested in understanding the role of epigenetics and spatial genome organization in this process. Geert Kops Group. 3584 CT Utrecht Chromatin cartographer EMBL alumnus Jop Kind, this year’s John Kendrew Award winner, reflects on … About the Hubrecht Institute Hubrecht Institute launches new website! j.kind@hubrecht.eu. This method enables linking transcriptional variability to epigenetic heterogeneity. Furthermore, as we consider technology development a core business of the group, we are continuously exploring ways to obtain richer single-cell datasets. Sort. In addition, we profile the epigenetic landscapes, chromatin accessibility and transcriptome in single cells. Bob Roberts 2020-06-07 16:21:36 ? 23. Royal Netherlands Academy of Arts & Sciences (KNAW) Phone +31 (0)30 212 1800; Email communication@hubrecht.eu; Website http://www.hubrecht.eu/ Oncode, starting from a deeper understanding of the basics of cancer, works to come up with better treatments and improved diagnostics. Oncode is an independent institute dedicated to understanding cancer and translating research into practice. ERC-starting grant for Marvin Tanenbaum and Jop Kind Marvin Tanenbaum and Jop Kind, both group leader at the Hubrecht Institute, are awarded an ERC-starting grant. Jop Kind EMBL: Predoc, Akhtar group, Genome Biology, 2002-2008. Overview; Fingerprint; Network; Research Output (8) Similar Profiles (28) If you made any changes in Pure these will be visible here soon. Jobs. Seeing is sequencing: linking phenotypes and genotypes of heterogeneous cancer cells by high-throughput, microscopy-based single cell selection and functionally annotated single cell sequencing. Partnership Agreement for Pontiac School District - Free download as PDF File (.pdf) or read online for free. Institute of Molecular Biotechnology, Austrian academy of science. Contact. (Jop) Kind: Active at: The Netherlands Cancer Institute: Hubrecht Institute for Developmental Biology and Stem Cell Research: Email address: If you have any questions or problems regarding login, please contact narcis@dans.knaw.nl. Credit: Jop Kind, copyright Hubrecht Institute. Chromatin cartographer EMBL alumnus Jop Kind, this year’s John Kendrew Award winner, reflects on the imaginative questions that led him to the prize . 2 Oncode Institute, Hubrecht Institute-KNAW and University Medical Center Utrecht, Utrecht, The Netherlands. Publications 23. Sort by citations Sort by year Sort by title. In total the NWO has awarded 87 experienced researchers a Vidi grant worth 800,000 euros. Jop Kind Group. https://lnkd.in/ekB-EJy #outsmartingcancer Hubrecht Institute, Developmental Biology and Stem Cell Research Knipscheer and Kind receive prestigious ERC Consolidator grant hubrecht.eu Jop Kind The organization of DNA within the eukaryotic nucleus is important for cellular processes such as regulation of gene expression and repair of DNA damage. Jop Kind, group leader at the Hubrecht Institute, has been awarded the John Kendrew award. Other Annotations. Uppsalalaan 8 Jop Kind, Junior Group Leader at the Hubrecht Institute. Royal Netherlands Academy of Arts & Sciences (KNAW), Hubrecht Institute; 2015 2020. Because DamID-signals are stable and can be carried-over for multiple generations, we are also looking into ways to exploit this property of DamID to study DSB-repair in the context of cellular decision making. Geert Kops Group. We have developed scDam&T, a method to simultaneously capture protein-DNA interactions and transcriptomes in the same cell (Rooijers et al, 2019, Nature Biotechnology) (Figure 1). Former EMBL Genome Biology PhD student, Jop Kind, has been selected as this year’s John Kendrew Young Scientist Award winner for pioneering postdoctoral work in establishing novel technologies to map chromatin domains in single cells. He made visible how 6 feet of DNA is dispersed in a cell nucleus of 10 micrometres. Jop Kind Group Leader at Hubrecht Institute, Developmental Biology and Stem Cell Research Amsterdam en omgeving, Nederland Meer dan 500 connecties jop kind Hubrecht Institute Verified email at hubrecht.eu. Reads . Nicolas Rivron. The European Research Council (ERC) awards grants to individual scientists of all nationalities and ages who perform groundbreaking research. The grant allows her to expand her group with 4 researchers for the duration of 5 years. 2 day event 19 - 20 Apr. Nederland, © Copyright 2021 Privacypolicy Hubrecht Institute, A major interest in the group is how gene-expression control is achieved in early embryogenesis. Read more | 5 November . Over 17 years of experience in Molecular Biology, Yuva completed her MSc. 2 Oncode Institute, Hubrecht Institute-KNAW and University Medical Center Utrecht, Utrecht, The Netherlands. “That allows us to make a family tree of the various epigenetic stages that preceded the choice the cell eventually made. By Jop Kind, Hubrecht Institute. Best Cities for Jobs 2020 NEW! Salaries, reviews and more - all posted by employees working at Hubrecht Institute. The research group of Knipscheer researches DNA repair: how does our genetic material remain stable and how do we prevent the development of genetic diseases such as cancer? Contact. Chromosomal regions that associate with a thin filamentous lamina layer at the nuclear periphery are generally in an inactive transcriptional state (Guerreiro and Kind, 2019, Curr.Opin.Gen.Dev.). Biomedical genomics; Hubrecht Institute. Because DamID-signals are stable and can be carried-over for multiple generations, we are also looking into ways to exploit this property of DamID to study DSB-repair in the context of cellular decision making. More information. Publications 23. Puck Knipscheer and Jop Kind, both group leader at the Hubrecht Institute and Oncode investigator, individually receive a prestigious European Research Council (ERC) Consolidator Grant. The following articles are merged in Scholar. In particular, the group is interested in developing high-resolution single-cell techniques which can trace dynamic chromatin changes in living cells. Currently, there are more than 70 PhD students at the Hubrecht Institute. Further, in the same cells, we also profile genome-wide chromatin states with a chromatin immunocleavage (ChIC) approach to study the relationships between DSB-repair and the local chromatin environment (Figure 3). ); s.kefalopoulou@hubrecht.eu (S.K.) Oncode unites science, collaboration and valorization to create impact for patients. See what employees say about what it's like to work at Hubrecht Institute. KIT, Royal Tropical Institute. Wouter de Laat Group. Cited by. Former EMBL Genome Biology PhD student, Jop Kind, has been selected as this year’s John Kendrew Young Scientist Award winner for pioneering postdoctoral work in establishing novel technologies to … Hubrecht Institute, NL. Molecular biologist dr. Jop Kind (1978) joined the Van Steensel lab as a postdoc after a highly successful PhD at the EMBL. The grant was awarded to only 327 out of 2506 applicants. Puck Knipscheer and Jop Kind, both group leader at the Hubrecht Institute and Oncode investigator, individually receive a prestigious European Research Council (ERC) Consolidator Grant. Jop Kind is group leader at the Hubrecht Institute and Oncode Investigator. Technology development Anna Kicheva IST Austria Verified email at ist.ac.at. Despite extensive research into the molecular pathways that sense and repair DNA double-strand breaks (DSBs), comparatively little is known about management of breaks within different genomic and chromatin contexts. A. Lochs †, Samy Kefalopoulou † and Jop Kind * Oncode Institute, Hubrecht Institute–KNAW and University Medical Center Utrecht, 3584 Utrecht, Over 17 years of experience in Molecular Biology, Yuva completed her MSc. Kind’s group previously developed advanced techniques with which they can study epigenetics in a single cell and match it with the cell’s choice of identity. Hubrecht Institute, Developmental Biology and Stem Cell Research | 6,134 followers on LinkedIn. Visit Kind's page. To be announced. 7 Oncode Institute, Hubrecht Institute-KNAW and University Medical Center Utrecht, Utrecht, the Netherlands. This is harmful because it prevents the DNA from replicating and thereby makes it impossible for cells to divide. Jop Kind is group leader at the Hubrecht Institute and Oncode investigator. Jop Kind, Group Leader at Hubrecht Institute and Oncode Investigator, will bring you up to speed with the basics of Single Cell Technology. Verified email at hubrecht.eu. Jop is currently an associate professor at the Hubrecht Institute in Utrecht where his lab continues to develop new techniques to single-cell profile gene-regulation to obtain better insights into the mechanisms that govern cell fate choice in development and disease. Online event. Read more | 11 November . We use this approach to understand how gene-expression is controlled and to obtain insight into the regulatory mechanisms that govern cellular decision making in mouse early embryogenesis. 13:05. In this conversation. 2 day event 19 - 20 Apr. Despite extensive research into the molecular pathways that sense and repair DNA double-strand breaks (DSBs), comparatively little is known about management of breaks within different genomic and chromatin contexts. Dive into the research topics where Jop Kind is active. A. Lochs †, Samy Kefalopoulou † and Jop Kind * Oncode Institute, Hubrecht Institute–KNAW and University Medical Center Utrecht, 3584 Utrecht, The Netherlands; s.lochs@hubrecht.eu (S.J.A.L. Wednesday 22 July. Since October 2014 he is Junior Group Leader at the Hubrecht Institute. The grant enables them to develop their own innovative line of research and set up their own research group. Erasmus University Medical Center/ UFO Biosciences, NL . Follow. As a postdoctoral fellow in the lab of Bas van Steensel at the NKI, Jop developed novel techniques to visualize and profile single-cell spatial genome organization. Kim L de Luca 1 , Jop Kind 2 ... 1 Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences (KNAW), University Medical Center Utrecht and Oncode Institute, Utrecht, The Netherlands. An important contributor to the regulation of gene expression is the spatial positioning of genes within the 3-dimensional space of the nucleus. Miao-Ping Chien. Annual Scientific Meeting. Save the date! ERC-starting grant for Marvin Tanenbaum and Jop Kind. Annual Scientific Meeting. Jop Kind lab. 2 day event 04 - 05 Nov. Oncode - CGC Annual Conference: Basic biology meets Cancer research. Cell-fate decisions and the role of epigenetics in DNA double-strand repair 2 day event 04 - 05 Nov. Oncode - CGC Annual Conference: Basic biology meets Cancer research . Projects 1. KIT, Royal Tropical Institute. PMID: 32350457 DOI: 10.1038/s41596-020-0314-8 Hubrecht Institute, NL. Susanne Lens Group. Spatiotemporal regulation of genomic function; Hubrecht Institute. In addition, scDam&T allows determining cellular identity of cells in complex tissues -such as embryos or tumors- based on transcriptomics, in direct relation to their epigenetic regulatory landscapes (DamID). Hubrecht Institute Summary: ... but instead attached to the ceiling at anchor points," says Jop Kind, group leader at the Hubrecht Institute. 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